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Crystal structure-based virtual screening for novel fragment-like ligands of the human histamine H(1) receptor
The recent crystal structure determinations of druggable class A G protein-coupled receptors (GPCRs) has opened up excellent opportunities in structure-based ligand discovery for this pharmaceutically important protein family. We have developed and validated a customized structure-based virtual frag...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228891/ https://ncbi.nlm.nih.gov/pubmed/22007643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2011589 |
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