A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design

BACKGROUND AND PURPOSE: Chemogenomics focuses on the discovery of new connections between chemical and biological space leading to the discovery of new protein targets and biologically active molecules. G-protein coupled receptors (GPCRs) are a particularly interesting protein family for chemogenomi...

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Main Authors: Kooistra, A J, Kuhne, S, de Esch, I J P, Leurs, R, de Graaf, C
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
Assuntos:
Themed Issue: Histamine Pharmacology Update
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764853/
https://ncbi.nlm.nih.gov/pubmed/23713847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12248
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