Central action of dendrotoxin: selective reduction of a transient K conductance in hippocampus and binding to localized acceptors.

Dendrotoxin, a small single-chain protein from the venom of Dendroaspis angusticeps, is highly toxic following intracerebroventricular injection into rats. Voltage-clamp analysis of CA1 neurons in hippocampal slices, treated with tetrodotoxin, revealed that nanomolar concentrations of dendrotoxin re...

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Hlavní autoři: Halliwell, J V, Othman, I B, Pelchen-Matthews, A, Dolly, J O
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC322886/
https://ncbi.nlm.nih.gov/pubmed/2417246
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