Central action of dendrotoxin: selective reduction of a transient K conductance in hippocampus and binding to localized acceptors.
Dendrotoxin, a small single-chain protein from the venom of Dendroaspis angusticeps, is highly toxic following intracerebroventricular injection into rats. Voltage-clamp analysis of CA1 neurons in hippocampal slices, treated with tetrodotoxin, revealed that nanomolar concentrations of dendrotoxin re...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1986
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.493 |
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