Central action of dendrotoxin: selective reduction of a transient K conductance in hippocampus and binding to localized acceptors.

Dendrotoxin, a small single-chain protein from the venom of Dendroaspis angusticeps, is highly toxic following intracerebroventricular injection into rats. Voltage-clamp analysis of CA1 neurons in hippocampal slices, treated with tetrodotoxin, revealed that nanomolar concentrations of dendrotoxin re...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Halliwell, J V, Othman, I B, Pelchen-Matthews, A, Dolly, J O
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.493
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