Tityustoxin K alpha blocks voltage-gated noninactivating K+ channels and unblocks inactivating K+ channels blocked by alpha-dendrotoxin in synaptosomes.

Two nonhomologous polypeptide toxins, tityustoxin K alpha (TsTX-K alpha) and tityustoxin K beta (TsTX-K beta), purified from the venom of the Brazilian scorpion Tityus serrulatus, selectively block voltage-gated noninactivating K+ channels in synaptosomes (IC50 values of 8 nM and 30 nM, respectively...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Rogowski, R S, Krueger, B K, Collins, J H, Blaustein, M P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43182/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509073/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1475
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