A role for hydrophobic residues in the voltage-dependent gating of Shaker K+ channels.

A leucine heptad repeat is well conserved in voltage-dependent ion channels. Herein we examine the role of the repeat region in Shaker K+ channels through substitution of the leucines in the repeat and through coexpression of normal and truncated products. In contrast to leucine-zipper DNA-binding p...

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Main Authors: McCormack, K, Tanouye, M A, Iverson, L E, Lin, J W, Ramaswami, M, McCormack, T, Campanelli, J T, Mathew, M K, Rudy, B
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC51354/
https://ncbi.nlm.nih.gov/pubmed/2011602
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