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A role for hydrophobic residues in the voltage-dependent gating of Shaker K+ channels.

A leucine heptad repeat is well conserved in voltage-dependent ion channels. Herein we examine the role of the repeat region in Shaker K+ channels through substitution of the leucines in the repeat and through coexpression of normal and truncated products. In contrast to leucine-zipper DNA-binding p...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: McCormack, K, Tanouye, M A, Iverson, L E, Lin, J W, Ramaswami, M, McCormack, T, Campanelli, J T, Mathew, M K, Rudy, B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2011602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.7.2931
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