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Astrocytes in aged non-human primate brain gray matter synthesize excess hyaluronan

The glycosaminoglycan hyaluronan (HA) accumulates in central nervous system lesions where it limits astrogliosis but also inhibits oligodendrocyte progenitor cell (OPC) maturation. The role of hyaluronan in normative brain aging has not been previously investigated. Here, we tested the hypothesis th...

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Detalhes bibliográficos
Main Authors: Cargill, Robert, Kohama, Steven G., Struve, Jaime, Su, Weiping, Banine, Fatima, Witkowski, Ellen, Back, Stephen A., Sherman, Larry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227765/
https://ncbi.nlm.nih.gov/pubmed/21872361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.07.006
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