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Astrocytes in aged non-human primate brain gray matter synthesize excess hyaluronan

The glycosaminoglycan hyaluronan (HA) accumulates in central nervous system lesions where it limits astrogliosis but also inhibits oligodendrocyte progenitor cell (OPC) maturation. The role of hyaluronan in normative brain aging has not been previously investigated. Here, we tested the hypothesis th...

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書誌詳細
主要な著者: Cargill, Robert, Kohama, Steven G., Struve, Jaime, Su, Weiping, Banine, Fatima, Witkowski, Ellen, Back, Stephen A., Sherman, Larry S.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227765/
https://ncbi.nlm.nih.gov/pubmed/21872361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.07.006
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