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Enhancement of Suboptimal CD8 Cytotoxic T Cell Effector Function In Vivo Using Antigen-Specific CD80 Defective T Cells

T cell upregulation of B7 molecules CD80 and CD86 limits T cell expansion in immunodeficient hosts; however, the relative roles of CD80 separate from CD86 on CD4 versus CD8 T cells in a normal immune system are not clear. To address this question, we used the parent-into-F1 (P→F1) murine model of gr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Puliaeva, Irina, Soloviova, Kateryna, Puliaiev, Maksym, Lang, Thomas, Puliaev, Roman, Via, Charles S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226733/
https://ncbi.nlm.nih.gov/pubmed/21115734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902370
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