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B cell depletion in murine lupus using cytotoxic T lymphocytes in vivo: feasibility and benefit.
Given the promising results in human lupus with B cell depletion, we tested whether in vivo cytotoxic T lymphocyte (CTL) could eliminate autoreactive B cells in the setting of murine lupus. Using the parent-into-F1 (P→F1) model to generate CTL that eliminate B cells, we found that transfer of NZB pa...
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| Опубликовано в: : | Cell Immunol |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7345861/ https://ncbi.nlm.nih.gov/pubmed/32408197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104117 |
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