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B cell depletion in murine lupus using cytotoxic T lymphocytes in vivo: feasibility and benefit.

Given the promising results in human lupus with B cell depletion, we tested whether in vivo cytotoxic T lymphocyte (CTL) could eliminate autoreactive B cells in the setting of murine lupus. Using the parent-into-F1 (P→F1) model to generate CTL that eliminate B cells, we found that transfer of NZB pa...

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Sonraí Bibleagrafaíochta
Foilsithe in:Cell Immunol
Main Authors: Soloviova, Kateryna, Puliaeva, Irina, Puliaiev, Maksym, Puliaev, Roman, Via, Charles S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345861/
https://ncbi.nlm.nih.gov/pubmed/32408197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104117
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