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Donor CD8 T Cells and IFN-γ Are Critical for Sex-Based Differences in Donor CD4 T Cell Engraftment and Lupus-Like Phenotype in Short-Term Chronic Graft-Versus-Host Disease Mice
The transfer of unfractionated DBA/2J (DBA) splenocytes into B6D2F(1) (DBA → F(1)) mice results in greater donor CD4 T cell engraftment in females at day 14 that persists long-term and mediates greater female lupus-like renal disease. Although donor CD8 T cells have no demonstrated role in lupus pat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215299/ https://ncbi.nlm.nih.gov/pubmed/21531893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001074 |
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