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In vivo IL-4 prevents allo-antigen driven CD8(+) CTL development
IL-4 has been shown to suppress acute graft vs. host disease (GVHD) in irradiated hosts. Here we evaluated whether IL-4 suppresses acute GVHD in the un-irradiated parent-into-F1 GVHD model with relevance to renal allograft rejection. IL-4 completely suppressed CD8 CTL when administered with donor ce...
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Publicado no: | Clin Immunol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484589/ https://ncbi.nlm.nih.gov/pubmed/28359782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2017.03.008 |
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