載入...

Cytotoxic T lymphocyte-promoting effects of CD40 stimulation outweigh B cell stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus

CD40/CD40L signaling promotes both B cell and CTL responses in vivo, the latter being beneficial in tumor models. Because CTL may also limit autoreactive B cell expansion in lupus, we asked whether an agonist CD40 mAb would exacerbate lupus due to B cell stimulation or would improve lupus due to CTL...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Puliaev, Roman, Puliaeva, Irina, Welniak, Lisbeth, Ryan, Abigail, Haas, Mark, Murphy, William, Via, Charles S.
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613003/
https://ncbi.nlm.nih.gov/pubmed/18566369
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!