Učitavanje...
Cytotoxic T lymphocyte-promoting effects of CD40 stimulation outweigh B cell stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus
CD40/CD40L signaling promotes both B cell and CTL responses in vivo, the latter being beneficial in tumor models. Because CTL may also limit autoreactive B cell expansion in lupus, we asked whether an agonist CD40 mAb would exacerbate lupus due to B cell stimulation or would improve lupus due to CTL...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613003/ https://ncbi.nlm.nih.gov/pubmed/18566369 |
| Oznake: |
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