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Fas expression on antigen-specific T cells has costimulatory, helper and downregulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses

Fas mediated apoptosis is an important contributor to contraction of ag-driven T cell responses acting only on activated ag-specific T cells. The effects of targeted Fas deletion on selected cell populations are well described however little is known regarding the consequences of Fas deletion on onl...

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Hlavní autoři: Puliaeva, Irina, Puliaev, Roman, Shustov, Andrei, Haas, Mark, Via, Charles S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775525/
https://ncbi.nlm.nih.gov/pubmed/18941180
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