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Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B

Type 1 phosphatase (PP1) antagonizes Aurora B kinase to stabilize kinetochore–microtubule attachments and to silence the spindle checkpoint. We screened for factors that exacerbate the growth defect of Δdis2 cells, which lack one of two catalytic subunits of PP1 in fission yeast, and identified Nsk1...

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Autors principals: Buttrick, Graham J., Meadows, John C., Lancaster, Theresa C., Vanoosthuyse, Vincent, Shepperd, Lindsey A., Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Hardwick, Kevin G., Millar, Jonathan B. A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226469/
https://ncbi.nlm.nih.gov/pubmed/21965289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-07-0608
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