Direct kinetochore–spindle pole connections are not required for chromosome segregation

Segregation of genetic material occurs when chromosomes move to opposite spindle poles during mitosis. This movement depends on K-fibers, specialized microtubule (MT) bundles attached to the chromosomes′ kinetochores. A long-standing assumption is that continuous K-fibers connect every kinetochore t...

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Détails bibliographiques
Auteurs principaux: Sikirzhytski, Vitali, Magidson, Valentin, Steinman, Jonathan B., He, Jie, Le Berre, Maël, Tikhonenko, Irina, Ault, Jeffrey G., McEwen, Bruce F., Chen, James K., Sui, Haixin, Piel, Matthieu, Kapoor, Tarun M., Khodjakov, Alexey
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2014
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107786/
https://ncbi.nlm.nih.gov/pubmed/25023516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201401090
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