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Kinetochore flexibility: creating a dynamic chromosome-spindle interface

Kinetochores are complex macromolecular assemblies that link chromosomes to the mitotic spindle, mediate forces for chromosome motion, and generate the checkpoint signal delaying anaphase onset until all chromosomes are incorporated into the spindle. Proper execution of these functions depends on pr...

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Détails bibliographiques
Auteurs principaux: O’Connell, Christopher B., Khodjakov, Alexey, McEwen, Bruce F.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507511/
https://ncbi.nlm.nih.gov/pubmed/22221609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2011.12.008
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