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Relative contributions of chromatin and kinetochores to mitotic spindle assembly
During mitosis and meiosis in animal cells, chromosomes actively participate in spindle assembly by generating a gradient of Ran guanosine triphosphate (RanGTP). A high concentration of RanGTP promotes microtubule nucleation and stabilization in the vicinity of chromatin. However, the relative contr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762104/ https://ncbi.nlm.nih.gov/pubmed/19805628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200903076 |
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