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Relative contributions of chromatin and kinetochores to mitotic spindle assembly

During mitosis and meiosis in animal cells, chromosomes actively participate in spindle assembly by generating a gradient of Ran guanosine triphosphate (RanGTP). A high concentration of RanGTP promotes microtubule nucleation and stabilization in the vicinity of chromatin. However, the relative contr...

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Detalhes bibliográficos
Main Authors: O'Connell, Christopher B., Lončarek, Jadranka, Kaláb, Petr, Khodjakov, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762104/
https://ncbi.nlm.nih.gov/pubmed/19805628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200903076
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