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Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells

Kinetochores attach chromosomes to the spindle microtubules and signal the spindle assembly checkpoint to delay mitotic exit until all chromosomes are attached. Light microscopy approaches aimed to indirectly determine distances between various proteins within the kinetochore (termed Delta) suggest...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Magidson, Valentin, He, Jie, Ault, Jeffrey G., O’Connell, Christopher B., Yang, Nachen, Tikhonenko, Irina, McEwen, Bruce F., Sui, Haixin, Khodjakov, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748573/
https://ncbi.nlm.nih.gov/pubmed/26833787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412139
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