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Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells

Kinetochores attach chromosomes to the spindle microtubules and signal the spindle assembly checkpoint to delay mitotic exit until all chromosomes are attached. Light microscopy approaches aimed to indirectly determine distances between various proteins within the kinetochore (termed Delta) suggest...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Magidson, Valentin, He, Jie, Ault, Jeffrey G., O’Connell, Christopher B., Yang, Nachen, Tikhonenko, Irina, McEwen, Bruce F., Sui, Haixin, Khodjakov, Alexey
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748573/
https://ncbi.nlm.nih.gov/pubmed/26833787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412139
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