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Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells

Kinetochores attach chromosomes to the spindle microtubules and signal the spindle assembly checkpoint to delay mitotic exit until all chromosomes are attached. Light microscopy approaches aimed to indirectly determine distances between various proteins within the kinetochore (termed Delta) suggest...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Magidson, Valentin, He, Jie, Ault, Jeffrey G., O’Connell, Christopher B., Yang, Nachen, Tikhonenko, Irina, McEwen, Bruce F., Sui, Haixin, Khodjakov, Alexey
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748573/
https://ncbi.nlm.nih.gov/pubmed/26833787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412139
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