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Chemical and Biological Approaches for Adapting Proteostasis to Ameliorate Protein Misfolding and Aggregation Diseases–Progress and Prognosis

Maintaining the proteome to preserve the health of an organism in the face of developmental changes, environmental insults, infectious diseases, and rigors of aging is a formidable task. The challenge is magnified by the inheritance of mutations that render individual proteins subject to misfolding...

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Detalhes bibliográficos
Main Authors: Lindquist, Susan L., Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225948/
https://ncbi.nlm.nih.gov/pubmed/21900404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a004507
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