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Chemical and/or Biological Therapeutic Strategies to Ameliorate Protein Misfolding Diseases
Inheriting a mutant misfolding-prone protein that cannot be efficiently folded in a given cell type(s) results in a spectrum of human loss-of-function misfolding diseases. The inability of the biological protein maturation pathways to adapt to a specific misfolding-prone protein also contributes to...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078197/ https://ncbi.nlm.nih.gov/pubmed/21146391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.11.002 |
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