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Chemical and Biological Approaches for Adapting Proteostasis to Ameliorate Protein Misfolding and Aggregation Diseases–Progress and Prognosis
Maintaining the proteome to preserve the health of an organism in the face of developmental changes, environmental insults, infectious diseases, and rigors of aging is a formidable task. The challenge is magnified by the inheritance of mutations that render individual proteins subject to misfolding...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225948/ https://ncbi.nlm.nih.gov/pubmed/21900404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a004507 |
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