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A Current Pharmacologic Agent versus The Promise of Next Generation Therapeutics to Ameliorate Protein Misfolding and/or Aggregation Diseases

The list of protein aggregation-associated degenerative diseases is long and growing, while the portfolio of disease-modifying strategies is very small. In this review and perspective, we assess what has worked to slow the progression of an aggregation-associated degenerative disease, covering the u...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: Baranczak, Aleksandra, Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907839/
https://ncbi.nlm.nih.gov/pubmed/26859714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2016.01.009
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