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Revealing the first uridyl peptide antibiotic biosynthetic gene cluster and probing pacidamycin biosynthesis

There is an urgent need for new antibiotics with resistance continuing to emerge toward existing classes. The pacidamycin antibiotics possess a novel scaffold and exhibit unexploited bioactivity rendering them attractive research targets. We recently reported the first identification of a biosynthet...

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Autors principals: Rackham, Emma J, Grüschow, Sabine, Goss, Rebecca JM
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225657/
https://ncbi.nlm.nih.gov/pubmed/21829097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.2.4.15877
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