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Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics
Pacidamycins are a family of uridyl tetra/pentapeptide antibiotics that act on the translocase MraY to block bacterial cell wall assembly. To elucidate the biosynthetic logic of pacidamcyins, a putative gene cluster was identified by 454 shotgun genome sequencing of the producer Streptomyces coerule...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947877/ https://ncbi.nlm.nih.gov/pubmed/20826445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011557107 |
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