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Revealing the first uridyl peptide antibiotic biosynthetic gene cluster and probing pacidamycin biosynthesis

There is an urgent need for new antibiotics with resistance continuing to emerge toward existing classes. The pacidamycin antibiotics possess a novel scaffold and exhibit unexploited bioactivity rendering them attractive research targets. We recently reported the first identification of a biosynthet...

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Detalhes bibliográficos
Main Authors: Rackham, Emma J, Grüschow, Sabine, Goss, Rebecca JM
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225657/
https://ncbi.nlm.nih.gov/pubmed/21829097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.2.4.15877
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