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Stereocontrolled Syntheses of Peptide Thioesters Containing Modified Seryl Residues as Probes of Antibiotic Biosynthesis

[Image: see text] Methods have been developed to synthesize tri- and pentapeptide thioesters containing one or more p-(hydroxyphenyl)glycine (pHPG) residues and L-serine, some where the latter is O-phosphorylated, O-acetylated or exists as a β-lactam. Selection of orthogonal protection strategies an...

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Detalhes bibliográficos
Main Authors: Gaudelli, Nicole M., Townsend, Craig A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898789/
https://ncbi.nlm.nih.gov/pubmed/23758494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo4007893
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