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RanGTP is required for meiotic spindle organization and the initiation of embryonic development in Drosophila

RanGTP is important for chromosome-dependent spindle assembly in Xenopus extracts. Here we report on experiments to determine the role of the Ran pathway on microtubule dynamics in Drosophila oocytes and embryos. Females expressing a dominant-negative form of Ran have fertility defects, suggesting t...

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Détails bibliographiques
Auteurs principaux: Cesario, J., McKim, K. S.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225268/
https://ncbi.nlm.nih.gov/pubmed/22100918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.084855
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