ISWI is a RanGTP-dependent MAP required for chromosome segregation

Production of RanGTP around chromosomes induces spindle assembly by activating nuclear localization signal (NLS)–containing factors. Here, we show that the NLS protein ISWI, a known chromatin-remodeling ATPase, is a RanGTP-dependent microtubule (MT)-associated protein. Recombinant ISWI induces MT nu...

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Detalhes bibliográficos
Main Authors: Yokoyama, Hideki, Rybina, Sofia, Santarella-Mellwig, Rachel, Mattaj, Iain W., Karsenti, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806316/
https://ncbi.nlm.nih.gov/pubmed/20008562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906020
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