Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate

Production of Ran–guanosine triphosphate (GTP) around chromosomes induces local nucleation and plus end stabilization of microtubules (MTs). The nuclear protein TPX2 is required for RanGTP-dependent MT nucleation. To find the MT stabilizer, we affinity purify nuclear localization signal (NLS)–contai...

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書誌詳細
主要な著者: Yokoyama, Hideki, Gruss, Oliver J., Rybina, Sofia, Caudron, Maïwen, Schelder, Malgorzata, Wilm, Matthias, Mattaj, Iain W., Karsenti, Eric
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2008
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265385/
https://ncbi.nlm.nih.gov/pubmed/18316407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706189
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