Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate

Production of Ran–guanosine triphosphate (GTP) around chromosomes induces local nucleation and plus end stabilization of microtubules (MTs). The nuclear protein TPX2 is required for RanGTP-dependent MT nucleation. To find the MT stabilizer, we affinity purify nuclear localization signal (NLS)–contai...

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Bibliografische gegevens
Hoofdauteurs: Yokoyama, Hideki, Gruss, Oliver J., Rybina, Sofia, Caudron, Maïwen, Schelder, Malgorzata, Wilm, Matthias, Mattaj, Iain W., Karsenti, Eric
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2008
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265385/
https://ncbi.nlm.nih.gov/pubmed/18316407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706189
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