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Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
Production of Ran–guanosine triphosphate (GTP) around chromosomes induces local nucleation and plus end stabilization of microtubules (MTs). The nuclear protein TPX2 is required for RanGTP-dependent MT nucleation. To find the MT stabilizer, we affinity purify nuclear localization signal (NLS)–contai...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265385/ https://ncbi.nlm.nih.gov/pubmed/18316407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706189 |
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