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ISWI is a RanGTP-dependent MAP required for chromosome segregation
Production of RanGTP around chromosomes induces spindle assembly by activating nuclear localization signal (NLS)–containing factors. Here, we show that the NLS protein ISWI, a known chromatin-remodeling ATPase, is a RanGTP-dependent microtubule (MT)-associated protein. Recombinant ISWI induces MT nu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806316/ https://ncbi.nlm.nih.gov/pubmed/20008562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906020 |
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