Rescue of Severe Infantile Hypophosphatasia Mice by AAV-Mediated Sustained Expression of Soluble Alkaline Phosphatase

Hypophosphatasia (HPP) is an inherited disease caused by a deficiency of tissue-nonspecific alkaline phosphatase (TNALP). The major symptom of human HPP is hypomineralization, rickets, or osteomalacia, although the clinical severity is highly variable. The phenotypes of TNALP knockout (Akp2(-/-)) mi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Matsumoto, Tae, Miyake, Koichi, Yamamoto, Seiko, Orimo, Hideo, Miyake, Noriko, Odagaki, Yuko, Adachi, Kumi, Iijima, Osamu, Narisawa, Sonoko, Millán, José Luis, Fukunaga, Yoshitaka, Shimada, Takashi
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225041/
https://ncbi.nlm.nih.gov/pubmed/21388343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.210
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars