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Alkaline Phosphatase and Hypophosphatasia
Hypophosphatasia (HPP) results from ALPL mutations leading to deficient activity of the tissue-non-specific alkaline phosphatase isozyme (TNAP) and thereby extracellular accumulation of inorganic pyrophosphate (PP(i)), a natural substrate of TNAP and potent inhibitor of mineralization. Thus, HPP fea...
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| Publicado no: | Calcif Tissue Int |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824800/ https://ncbi.nlm.nih.gov/pubmed/26590809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-015-0079-1 |
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