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Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms()

The microtubule-associated protein tau exists as six isoforms created through the splicing of the second, third, and tenth exons. The isoforms are classified by their number of N-terminal exons (0N, 1N or 2N) and by their number of microtubule-binding repeat regions (3R or 4R). Hyperphosphorylated i...

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Hlavní autoři: Combs, Benjamin, Voss, Kellen R., Gamblin, T. Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224825/
https://ncbi.nlm.nih.gov/pubmed/21942206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2010569
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