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GSK-3β phosphorylation of functionally distinct tau isoforms has differential, but mild effects
BACKGROUND: Tau protein exists as six different isoforms that differ by the inclusion or exclusion of exons 2, 3 and 10. Exon 10 encodes a microtubule binding repeat, thereby resulting in three isoforms with three microtubule binding repeats (3R) and three isoforms that have four microtubule binding...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
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BioMed Central
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683827/ https://ncbi.nlm.nih.gov/pubmed/19409104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-4-18 |
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