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Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms()
The microtubule-associated protein tau exists as six isoforms created through the splicing of the second, third, and tenth exons. The isoforms are classified by their number of N-terminal exons (0N, 1N or 2N) and by their number of microtubule-binding repeat regions (3R or 4R). Hyperphosphorylated i...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224825/ https://ncbi.nlm.nih.gov/pubmed/21942206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2010569 |
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