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Hsp70 alters tau function and aggregation in an isoform specific manner()
Tauopathies are characterized by abnormal aggregation of the microtubule associated protein tau. This aggregation is thought to occur when tau undergoes shifts from its native conformation to one that exposes hydrophobic areas on separate monomers, allowing contact and subsequent association into ol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278803/ https://ncbi.nlm.nih.gov/pubmed/22236337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2018078 |
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