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Identification of Cytotoxic Drugs That Selectively Target Tumor Cells with MYC Overexpression

Expression of MYC is deregulated in a wide range of human cancers, and is often associated with aggressive disease and poorly differentiated tumor cells. Identification of compounds with selectivity for cells overexpressing MYC would hence be beneficial for the treatment of these tumors. For this pu...

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Detalhes bibliográficos
Main Authors: Frenzel, Anna, Zirath, Hanna, Vita, Marina, Albihn, Ami, Henriksson, Marie Arsenian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223192/
https://ncbi.nlm.nih.gov/pubmed/22132187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027988
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