MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

The MYC genes are the most frequently activated oncogenes in human tumors and are hence attractive therapeutic targets. MYCN amplification leads to poor clinical outcome in childhood neuroblastoma, yet strategies to modulate the function of MYCN do not exist. Here we show that 10058-F4, a characteri...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Zirath, Hanna, Frenzel, Anna, Oliynyk, Ganna, Segerström, Lova, Westermark, Ulrica K., Larsson, Karin, Munksgaard Persson, Matilda, Hultenby, Kjell, Lehtiö, Janne, Einvik, Christer, Påhlman, Sven, Kogner, Per, Jakobsson, Per-Johan, Arsenian Henriksson, Marie
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690852/
https://ncbi.nlm.nih.gov/pubmed/23733953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222404110
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars