COX/mPGES-1/PGE(2) pathway depicts an inflammatory-dependent high-risk neuroblastoma subset

The majority of solid tumors are presented with an inflammatory microenvironment. Proinflammatory lipid mediators including prostaglandin E(2) (PGE(2)) contribute to the establishment of inflammation and have been linked to tumor growth and aggressiveness. Here we show that high-risk neuroblastoma w...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Larsson, Karin, Kock, Anna, Idborg, Helena, Arsenian Henriksson, Marie, Martinsson, Tommy, Johnsen, John I., Korotkova, Marina, Kogner, Per, Jakobsson, Per-Johan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491767/
https://ncbi.nlm.nih.gov/pubmed/26080408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424355112
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