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Identification of Cytotoxic Drugs That Selectively Target Tumor Cells with MYC Overexpression

Expression of MYC is deregulated in a wide range of human cancers, and is often associated with aggressive disease and poorly differentiated tumor cells. Identification of compounds with selectivity for cells overexpressing MYC would hence be beneficial for the treatment of these tumors. For this pu...

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Библиографические подробности
Главные авторы: Frenzel, Anna, Zirath, Hanna, Vita, Marina, Albihn, Ami, Henriksson, Marie Arsenian
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223192/
https://ncbi.nlm.nih.gov/pubmed/22132187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027988
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