N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles

For effective airway gene therapy of cystic fibrosis (CF), inhaled gene carriers must first penetrate the hyperviscoelastic sputum covering the epithelium. Whether clinically studied gene carriers can penetrate CF sputum remains unknown. Here, we measured the diffusion of a clinically tested nonvira...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Suk, Jung Soo, Boylan, Nicholas J, Trehan, Kanika, Tang, Benjamin C, Schneider, Craig S, Lin, Jung-Ming G, Boyle, Michael P, Zeitlin, Pamela L, Lai, Samuel K, Cooper, Mark J, Hanes, Justin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222526/
https://ncbi.nlm.nih.gov/pubmed/21829177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.160
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak