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PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro
End-directed mismatch-provoked excision has been reconstituted in several purified systems. While 3′-directed excision displays a mismatch dependence similar to that observed in nuclear extracts (≈ 20-fold), the mismatch dependence of 5′-directed excision is only 3 to 4-fold, significantly less than...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222275/ https://ncbi.nlm.nih.gov/pubmed/21945626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.08.012 |
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