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HUMAN MISMATCH REPAIR: RECONSTITUTION OF A NICK-DIRECTED BIDIRECTIONAL REACTION

Bidirectional mismatch repair directed by a strand break located 3′ or 5′ to the mispair has been reconstituted using seven purified human activities: MutSα, MutLα, EXOI, RPA, PCNA, RFC, and DNA polymerase δ. In addition to DNA polymerase δ, PCNA, RFC, and RPA, 5′-directed repair depends on MutSα an...

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Detalhes bibliográficos
Main Authors: Constantin, Nicoleta, Dzantiev, Leonid, Kadyrov, Farid A., Modrich, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435381/
https://ncbi.nlm.nih.gov/pubmed/16188885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509701200
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