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PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro

End-directed mismatch-provoked excision has been reconstituted in several purified systems. While 3′-directed excision displays a mismatch dependence similar to that observed in nuclear extracts (≈ 20-fold), the mismatch dependence of 5′-directed excision is only 3 to 4-fold, significantly less than...

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Bibliografski detalji
Glavni autori: Liu, Yiyong, Kadyrov, Farid A., Modrich, Paul
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222275/
https://ncbi.nlm.nih.gov/pubmed/21945626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.08.012
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